Gene
cfl2
- ID
- ZDB-GENE-040426-1815
- Name
- cofilin 2 (muscle)
- Symbol
- cfl2 Nomenclature History
- Previous Names
-
- zgc:77288
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have actin binding activity. Predicted to be involved in actin filament depolymerization. Predicted to localize to actin cytoskeleton. Human ortholog(s) of this gene implicated in nemaline myopathy 7. Is expressed in lens; myotome; solid lens vesicle; and somite. Orthologous to human CFL2 (cofilin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6909063 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nemaline myopathy 7 | Alliance | Nemaline myopathy 7, autosomal recessive | 610687 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Actin-depolymerising factor homology domain | ADF/Cofilin | ADF-H/Gelsolin-like domain superfamily |
|---|---|---|---|---|
|
UniProtKB:Q6NZW3
|
166 |
Interactions and Pathways
No data available
Plasmids
No data available