Gene
ndufv2
- ID
- ZDB-GENE-040426-1713
- Name
- NADH:ubiquinone oxidoreductase core subunit V2
- Symbol
- ndufv2 Nomenclature History
- Previous Names
-
- zgc:73198
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to localize to mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Parkinson's disease and mitochondrial complex I deficiency. Is expressed in several structures, including alar plate midbrain region; digestive system; optic tectum; optic vesicle; and retina. Orthologous to human NDUFV2 (NADH:ubiquinone oxidoreductase core subunit V2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73198 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nuclear type mitochondrial complex I deficiency 7 | Alliance | Mitochondrial complex I deficiency, nuclear type 7 | 618229 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | NADH-quinone oxidoreductase subunit E-like | NADH-quinone oxidoreductase subunit E, N-terminal | NuoE domain | Thioredoxin-like superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q6PBX8
|
244 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available