Gene

amph

ID

ZDB-GENE-040426-1711

Name

amphiphysin

Symbol

amph Nomenclature History

Previous Names

wu:fq25h04
zgc:73193 (1)

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have phospholipid binding activity. Predicted to be involved in synaptic vesicle endocytosis. Localizes to cytoplasm. Is expressed in several structures, including fin; gonad; heart; nervous system; and neural tube. Orthologous to human AMPH (amphiphysin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

16 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With amph Human Ortholog

No data available

Associated With amph Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001452	SH3 domain
Domain	IPR004148	BAR domain
Domain	IPR035470	Amphiphysin I, SH3 domain
Family	IPR003005	Amphiphysin
Family	IPR003017	Amphiphysin, isoform 1
Homologous_superfamily	IPR027267	AH/BAR domain superfamily
Homologous_superfamily	IPR036028	SH3-like domain superfamily

Domain Details Per Protein

Protein	Length	AH/BAR domain superfamily	Amphiphysin	Amphiphysin I, SH3 domain	Amphiphysin, isoform 1	BAR domain	SH3 domain	SH3-like domain superfamily
UniProtKB:A0A8M9QKZ9 InterPro	1099
UniProtKB:A0A8M9QCD2 InterPro	1292
UniProtKB:A0A8M9QKZ5 InterPro	1110
UniProtKB:A0A0R4INS3 InterPro	691
UniProtKB:A0A8M9QGX1 InterPro	1231
UniProtKB:A0A8M3AXC2 InterPro	1305
UniProtKB:A0A8M9QL02 InterPro	1078
UniProtKB:A0A8M9QCE0 InterPro	1215
UniProtKB:A0A8M6Z8S2 InterPro	768
UniProtKB:A0A8M9PU06 InterPro	787
UniProtKB:A0A8M9QGX5 InterPro	1197
UniProtKB:A0A8M9QKX1 InterPro	1308
UniProtKB:A0A8M9PTW9 InterPro	1297
UniProtKB:A0A8M9Q6E4 InterPro	1274
UniProtKB:Q6P960 InterPro	784
UniProtKB:A0A8M9PU16 InterPro	589

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	amph-201 (1) Ensembl	Havana	3424 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	amph-002 (1) Ensembl	Havana	494 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations