Gene
mffa
- ID
- ZDB-GENE-040426-1510
- Name
- mitochondrial fission factor a
- Symbol
- mffa Nomenclature History
- Previous Names
-
- mff
- zgc:66022
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have protein homodimerization activity. Predicted to be involved in mitochondrial fission; positive regulation of mitochondrial fission; and positive regulation of protein targeting to membrane. Predicted to localize to peroxisome. Human ortholog(s) of this gene implicated in brain disease. Is expressed in female organism. Orthologous to human MFF (mitochondrial fission factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66022 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Encephalopathy due to defective mitochondrial and peroxisomal fission 2 | 617086 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Mff-like domain | Mff/Tango-11 |
|---|---|---|---|
|
UniProtKB:A0A8M9QH49
|
227 | ||
|
UniProtKB:A0A8M2B4R4
|
303 | ||
|
UniProtKB:Q7SZQ4
|
230 | ||
|
UniProtKB:A0A8M2B4M8
|
248 |
Interactions and Pathways
No data available
Plasmids
No data available