Gene
mtap
- ID
- ZDB-GENE-040426-1505
- Name
- methylthioadenosine phosphorylase
- Symbol
- mtap Nomenclature History
- Previous Names
-
- zgc:66012
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have S-methyl-5-thioadenosine phosphorylase activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in biliary tract benign neoplasm. Orthologous to human MTAP (methylthioadenosine phosphorylase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66012 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| diaphyseal medullary stenosis with malignant fibrous histiocytoma | Alliance | Diaphyseal medullary stenosis with malignant fibrous histiocytoma | 112250 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Methylthioadenosine phosphorylase (MTAP) | Nucleoside phosphorylase domain | Nucleoside phosphorylase superfamily | Purine phosphorylase, family 2, conserved site |
|---|---|---|---|---|---|
|
UniProtKB:B2GQM6
|
280 | ||||
|
UniProtKB:Q7ZV22
|
280 |
Interactions and Pathways
No data available
Plasmids
No data available