Gene

srsf1b

ID

ZDB-GENE-040426-1467

Name

serine and arginine rich splicing factor 1b

Symbol

srsf1b Nomenclature History

Previous Names

sfrs1 (1)
sfrs1b
wu:fb80g05
zgc:111894
zgc:65898
zgc:76897

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to have RNA binding activity. Predicted to be involved in mRNA cis splicing, via spliceosome and regulation of alternative mRNA splicing, via spliceosome. Predicted to localize to nuclear speck. Orthologous to human SRSF1 (serine and arginine rich splicing factor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:65898 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With srsf1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
neurodevelopmental disorder with dysmorphic facies and behavioral abnormalities	Alliance	Neurodevelopmental disorder with dysmorphic facies and behavioral abnormalities	620489

Associated With srsf1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR029538	Serine/arginine-rich splicing factor 1, RNA recognition motif 2
Domain	IPR034520	SRSF1, RNA recognition motif 1
Family	IPR050374	RRT5/SRSF/Splicing Factor SR
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily