Gene
bmp5
- ID
- ZDB-GENE-040426-1413
- Name
- bone morphogenetic protein 5
- Symbol
- bmp5 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have BMP receptor binding activity and cytokine activity. Involved in neural crest cell development; positive regulation of ERK1 and ERK2 cascade; and positive regulation of pathway-restricted SMAD protein phosphorylation. Predicted to localize to extracellular space. Is expressed in several structures, including neural crest; optic vesicle; periderm; pharyngeal arch; and sensory system. Orthologous to human BMP5 (bone morphogenetic protein 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:64230 (8 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017948 | Transforming growth factor beta, conserved site |
| Domain | IPR001111 | TGF-beta, propeptide |
| Domain | IPR001839 | Transforming growth factor-beta, C-terminal |
| Family | IPR015615 | Transforming growth factor-beta-related |
| Homologous_superfamily | IPR029034 | Cystine-knot cytokine |
Domain Details Per Protein
| Protein | Length | Cystine-knot cytokine | TGF-beta, propeptide | Transforming growth factor beta, conserved site | Transforming growth factor-beta, C-terminal | Transforming growth factor-beta-related |
|---|---|---|---|---|---|---|
|
UniProtKB:Q7T288
|
446 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available