Gene
diabloa
- ID
- ZDB-GENE-040426-1303
- Name
- diablo, IAP-binding mitochondrial protein a
- Symbol
- diabloa Nomenclature History
- Previous Names
-
- diablo
- smac (1)
- zgc:63938
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to be involved in activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; intrinsic apoptotic signaling pathway in response to oxidative stress; and neuron apoptotic process. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 64. Is expressed in several structures, including cardiovascular system; digestive system; lens; pectoral fin; and solid lens vesicle. Orthologous to human DIABLO (diablo IAP-binding mitochondrial protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7162253 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant nonsyndromic deafness 64 | Alliance | Deafness, autosomal dominant 64 | 614152 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Smac/DIABLO-like superfamily | Smac/DIABLO protein |
|---|---|---|---|
|
UniProtKB:Q7T3E1
|
265 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
diabloa-202
(1)
|
Ensembl | 1,478 nt | ||
| mRNA |
diabloa-204
(1)
|
Ensembl | 895 nt | ||
| ncRNA |
diabloa-002
(1)
|
Ensembl | 791 nt | ||
| ncRNA |
diabloa-003
(1)
|
Ensembl | 887 nt |
Interactions and Pathways
No data available
Plasmids
No data available