Gene
srfb
- ID
- ZDB-GENE-040426-1294
- Name
- serum response factor b
- Symbol
- srfb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; cis-regulatory region sequence-specific DNA binding activity; and protein dimerization activity. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in cardiovascular system; digestive system; myotome; segmental plate; and somite. Human ortholog(s) of this gene implicated in cardiomyopathy and lymphangioleiomyomatosis. Orthologous to human SRF (serum response factor).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 6 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63911 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | MADS-box/MEF2 Transcription Factor | MADS SRF-like | Transcription factor, MADS-box | Transcription factor, MADS-box superfamily |
---|---|---|---|---|---|
UniProtKB:Q6PFU5
|
314 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available