ZFIN ID: ZDB-GENE-040426-1262
Gene Name: aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1
Gene Symbol: aldh2.1
Previous Names: aldh2 (1), aldh2a, zgc:63786
Location: Chr: 5   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Adult (90d-730d, breeding adult)
  brain, caudal fin, eye, gill (all 13) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-aldh2.1 (1)
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Alcohol sensitivity, acute 610251
{Esophageal cancer, alcohol-related, susceptibility to}
{Hangover, susceptibility to} 610251
{Sublingual nitroglycerin, susceptibility to poor response to}
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component cellular_component (more)
Molecular Function 3-chloroallyl aldehyde dehydrogenase activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR015590 (1)
  • InterPro:IPR016160 (1)
  • InterPro:IPR016161 (1)
  • InterPro:IPR016162 (1)
  • InterPro:IPR016163 (1)
  • InterPro:IPR029510 (1)
  • PROSITE:PS00070 (1)
  • PROSITE:PS00687 (1)
  • Pfam:PF00171 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA aldh2.1-001 (1) 1935
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM aldh2.1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    aldh2.1 Contained in: [BAC] CH211-157P22 (1) (order this), DKEY-204G14 (1)
    aldh2.1 Encodes: [cDNA] MGC:63786 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200490 (1) 1940 bp
    Genomic GenBank:CT978957 (1) 164556 bp
    Select Tool
    Polypeptide UniProtKB:A2BGR9 (1) 516 aa
    Sequence Clusters UniGene:28434 (1)
    Sequence Information (all 13)
    OTHER aldh2.1 GENE PAGES
  • Gene:393462 (1)
  • VEGA:OTTDARG00000018931 (1)
  • Ensembl(Zv9):ENSDARG00000089924 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish aldh2.1 5  
    Human ALDH2 12 (12q24.2)
  • OMIM:100650
  • Gene:217
  • Mouse Aldh2 5 ( 61.86 cM)
  • MGI:99600
  • Gene:11669
  • Orthology Details
    CITATIONS (24)