Gene

cyp46a1.4

ID
ZDB-GENE-040426-1224
Name
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4
Symbol
cyp46a1.4 Nomenclature History
Previous Names
  • cyp46a4
  • zgc:63667
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have cholesterol 24-hydroxylase activity and heme binding activity. Predicted to be involved in cholesterol catabolic process. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CYP46A1 (cytochrome P450 family 46 subfamily A member 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cyp46a1.4 Human Ortholog
No data available
Associated With cyp46a1.4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001128 Cytochrome P450
Family IPR002401 Cytochrome P450, E-class, group I
Family IPR039983 Cholesterol 24-hydroxylase
Homologous_superfamily IPR036396 Cytochrome P450 superfamily
Domain Details Per Protein
Protein Length Cholesterol 24-hydroxylase Cytochrome P450 Cytochrome P450, E-class, group I Cytochrome P450 superfamily
UniProtKB:A0A0N4SUD5 501
UniProtKB:Q7SXY7 444
UniProtKB:A0A8M2B763 501
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations