Gene

stk10

ID

ZDB-GENE-040426-1136

Name

serine/threonine kinase 10

Symbol

stk10 Nomenclature History

Previous Names

zgc:63495

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to enable protein homodimerization activity and protein serine/threonine kinase activity. Predicted to be involved in protein autophosphorylation and regulation of lymphocyte migration. Predicted to act upstream of or within protein phosphopantetheinylation. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including EVL; epidermis; hatching gland; mesoderm; and periderm. Orthologous to human STK10 (serine/threonine kinase 10).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:63495 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With stk10 Human Ortholog

No data available

Associated With stk10 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR042743	Serine/threonine-protein kinase 10, catalytic domain
Family	IPR022165	Polo kinase kinase
Family	IPR051585	STE20 Subfamily Serine/Threonine Kinases
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily

Domain Details Per Protein

Protein	Length	Polo kinase kinase	Protein kinase, ATP binding site	Protein kinase domain	Protein kinase-like domain superfamily	Serine/threonine-protein kinase 10, catalytic domain	Serine/threonine-protein kinase, active site	STE20 Subfamily Serine/Threonine Kinases
UniProtKB:Q7SY52 InterPro	974

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	stk10-201 (1) Ensembl	Ensembl		2,704 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations