Gene

idh3a

ID

ZDB-GENE-040426-1007

Name

isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha

Symbol

idh3a Nomenclature History

Previous Names

zgc:56380 (1)
zgc:85631

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to have isocitrate dehydrogenase (NAD+) activity. Predicted to be involved in isocitrate metabolic process and tricarboxylic acid cycle. Predicted to localize to mitochondrion. Is expressed in several structures, including alar plate midbrain region; mesoderm; musculature system; optic tectum; and pronephric duct. Orthologous to human IDH3A (isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:56380 (15 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With idh3a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
retinitis pigmentosa 90	Alliance	Retinitis pigmentosa 90	619007

Associated With idh3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019818	Isocitrate/isopropylmalate dehydrogenase, conserved site
Domain	IPR024084	Isopropylmalate dehydrogenase-like domain
Family	IPR004434	Isocitrate dehydrogenase NAD-dependent