Gene
rapgef1b
- ID
- ZDB-GENE-040426-1001
- Name
- Rap guanine nucleotide exchange factor (GEF) 1b
- Symbol
- rapgef1b Nomenclature History
- Previous Names
-
- rapgef1
- zgc:56372 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction and positive regulation of GTPase activity. Predicted to act upstream of or within small GTPase mediated signal transduction. Predicted to be active in plasma membrane. Orthologous to human RAPGEF1 (Rap guanine nucleotide exchange factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56372 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019804 | Ras guanine-nucleotide exchange factor, conserved site |
| Domain | IPR000651 | Ras-like guanine nucleotide exchange factor, N-terminal |
| Domain | IPR001895 | Ras guanine-nucleotide exchange factors catalytic domain |
| Family | IPR008937 | Ras-like guanine nucleotide exchange factor |
| Homologous_superfamily | IPR023578 | Ras guanine nucleotide exchange factor domain superfamily |
| Homologous_superfamily | IPR036964 | Ras guanine-nucleotide exchange factor, catalytic domain superfamily |
Domain Details Per Protein
| Protein | Length | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Ras guanine-nucleotide exchange factor, conserved site | Ras guanine nucleotide exchange factor domain superfamily | Ras guanine-nucleotide exchange factors catalytic domain | Ras-like guanine nucleotide exchange factor | Ras-like guanine nucleotide exchange factor, N-terminal |
|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F4B2
|
1188 | ||||||
|
UniProtKB:A0A8M9PQB1
|
1203 | ||||||
|
UniProtKB:A0A8M9PI61
|
1101 | ||||||
|
UniProtKB:A0A8M9P382
|
1183 | ||||||
|
UniProtKB:A0A8M9PTQ9
|
1204 | ||||||
|
UniProtKB:A0A8M9PCJ2
|
1155 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rapgef1b-201
(1)
|
Ensembl | 4,332 nt | ||
| mRNA |
rapgef1b-203
(1)
|
Ensembl | 1,710 nt | ||
| mRNA |
rapgef1b-204
(1)
|
Ensembl | 2,119 nt | ||
| ncRNA |
rapgef1b-003
(1)
|
Ensembl | 944 nt |
Interactions and Pathways
No data available
Plasmids
No data available