Gene
bcor
- ID
- ZDB-GENE-040408-1
- Name
- BCL6 corepressor
- Symbol
- bcor Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have transcription corepressor activity. Involved in negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; neural tube development; and retina morphogenesis in camera-type eye. Human ortholog(s) of this gene implicated in syndromic microphthalmia. Orthologous to human BCOR (BCL6 corepressor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Lee et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| syndromic microphthalmia 2 | Alliance | Microphthalmia, syndromic 2 | 300166 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR031628 | BCL-6 corepressor, non-ankyrin-repeat domain |
| Domain | IPR032365 | BCL-6 corepressor, PCGF1 binding domain |
| Family | IPR047144 | BCL-6 corepressor-like |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Homologous_superfamily | IPR038227 | PCGF Ub-like fold discriminator superfamily |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
| Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | BCL-6 corepressor-like | BCL-6 corepressor, non-ankyrin-repeat domain | BCL-6 corepressor, PCGF1 binding domain | PCGF Ub-like fold discriminator superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6W2J8
|
1777 | ||||||
|
UniProtKB:F1RCL8
|
1796 |
Interactions and Pathways
No data available
Plasmids
No data available