Gene

dab2

ID
ZDB-GENE-040303-1
Name
DAB adaptor protein 2
Symbol
dab2 Nomenclature History
Previous Names
  • sb:cb778
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Involved in several processes, including angiogenesis; regulation of cardiac muscle cell differentiation; and regulation of signal transduction. Predicted to localize to cytoplasm and plasma membrane. Is expressed in several structures, including intermediate cell mass of mesoderm; intestinal bulb; pronephros; vasculature; and ventral mesoderm. Orthologous to human DAB2 (DAB adaptor protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
48 figures from 34 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dab2 Human Ortholog
No data available
Associated With dab2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR048559 Disabled homolog 1/2, sulfatide-binding motif
Domain IPR006020 PTB/PI domain
Domain IPR048561 Disabled, phosphotyrosine-binding domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain Details Per Protein
Protein Length Disabled homolog 1/2, sulfatide-binding motif Disabled, phosphotyrosine-binding domain PH-like domain superfamily PTB/PI domain
UniProtKB:A0A8M1P9G4 797
UniProtKB:F6NGQ6 589
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations