Gene

phka1a

ID

ZDB-GENE-031118-56

Name

phosphorylase kinase, alpha 1a (muscle)

Symbol

phka1a Nomenclature History

Previous Names

phka1
wu:fl37h01

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to enable calmodulin binding activity. Predicted to be involved in glycogen metabolic process. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in glycogen storage disease and glycogen storage disease IXd. Orthologous to human PHKA1 (phosphorylase kinase regulatory subunit alpha 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With phka1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
glycogen storage disease IXd	Alliance	Muscle glycogenosis	300559

Associated With phka1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR011613	GH15-like domain
Domain	IPR045583	Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain
Family	IPR008734	Phosphorylase kinase alpha/beta subunit
Homologous_superfamily	IPR008928	Six-hairpin glycosidase superfamily
Homologous_superfamily	IPR012341	Six-hairpin glycosidase-like superfamily

Domain Details Per Protein

Protein	Length	GH15-like domain	Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain	Phosphorylase kinase alpha/beta subunit	Six-hairpin glycosidase-like superfamily	Six-hairpin glycosidase superfamily
UniProtKB:A0A286YAZ5 InterPro	1232
UniProtKB:E7F4R5 InterPro	1219
UniProtKB:A0A8M6Z7W8 InterPro	1201

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	hdac8-206 (1) Ensembl	Ensembl	5,150 nt	Select Tool ZFIN BLAST
mRNA	hdac8-207 (1) Ensembl	Ensembl	846 nt	Select Tool ZFIN BLAST
mRNA	hdac8-209 (1) Ensembl	Ensembl	7,589 nt	Select Tool ZFIN BLAST
mRNA	hdac8-210 (1) Ensembl	Ensembl	7,757 nt	Select Tool ZFIN BLAST
ncRNA	phka1a-002 (1) Ensembl	Ensembl	539 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations