Gene
fstb
- ID
- ZDB-GENE-031118-139
- Name
- follistatin b
- Symbol
- fstb Nomenclature History
- Previous Names
-
- fst2 (2)
- fstl
- hm:zeh1606
- zeh1606
- zgc:171342
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have activin binding activity. Predicted to be involved in cell differentiation; multicellular organism development; and regulation of transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in polycystic ovary syndrome. Is expressed in several structures, including brain; heart; integument; pharyngeal arch 3-7 skeleton; and somite. Orthologous to human FST (follistatin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002350 | Kazal domain |
| Domain | IPR003645 | Follistatin-like, N-terminal |
| Domain | IPR015369 | Follistatin/Osteonectin EGF domain |
| Domain | IPR017878 | TB domain |
| Homologous_superfamily | IPR036058 | Kazal domain superfamily |
| Homologous_superfamily | IPR036773 | TGF-beta binding (TB) domain superfamily |
Domain Details Per Protein
| Protein | Length | Follistatin-like, N-terminal | Follistatin/Osteonectin EGF domain | Kazal domain | Kazal domain superfamily | TB domain | TGF-beta binding (TB) domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q2PMI4
|
344 | ||||||
|
UniProtKB:A7MBP8
|
319 |
Interactions and Pathways
No data available
Plasmids
No data available