Gene

stam

ID

ZDB-GENE-031118-123

Name

signal transducing adaptor molecule (SH3 domain and ITAM motif) 1

Symbol

stam Nomenclature History

Previous Names

wu:fv75b10

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to be involved in protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to act upstream of or within intracellular protein transport. Predicted to be located in early endosome membrane. Predicted to be part of ESCRT-0 complex. Is expressed in immature eye and nervous system. Orthologous to human STAM (signal transducing adaptor molecule).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55725 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With stam Human Ortholog

No data available

Associated With stam Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR003903	Ubiquitin interacting motif
Domain	IPR001452	SH3 domain
Domain	IPR002014	VHS domain
Domain	IPR035657	STAM1, SH3 domain
Domain	IPR047492	STAM1, non-canonical GAT domain
Domain	IPR047528	STAM1, VHS domain
Family	IPR050670	Signal Transducing Adapter Molecule
Homologous_superfamily	IPR008942	ENTH/VHS
Homologous_superfamily	IPR036028	SH3-like domain superfamily