ZFIN is now using GRCz12tu for Genomic Data
Gene
scn4bb
- ID
- ZDB-GENE-031116-71
- Name
- sodium channel, voltage-gated, type IV, beta b
- Symbol
- scn4bb Nomenclature History
- Previous Names
-
- scn4b.2 (1)
- sb:cb973
- si:ch211-139a5.5
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable sodium channel regulator activity and transmembrane transporter binding activity. Predicted to be involved in cardiac conduction; cardiac muscle cell action potential; and regulation of ventricular cardiac muscle cell membrane repolarization. Predicted to be located in membrane. Predicted to be part of voltage-gated sodium channel complex. Predicted to be active in plasma membrane. Is expressed in cardiac ventricle; liver; nervous system; and solid lens vesicle. Human ortholog(s) of this gene implicated in long QT syndrome 10. Orthologous to human SCN4B (sodium voltage-gated channel beta subunit 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb973 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| long QT syndrome 10 | Alliance | Atrial fibrillation, familial, 17 | 611819 |
| long QT syndrome 10 | Alliance | Long QT syndrome 10 | 611819 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013106 | Immunoglobulin V-set domain |
| Family | IPR000920 | Myelin P0 protein-related |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin V-set domain | Myelin P0 protein-related |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q06W25 | InterPro | 232 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
scn4bb-201
(1)
|
Ensembl | 1,876 nt | ||
| mRNA |
scn4bb-202
(1)
|
Ensembl | 645 nt | ||
| mRNA |
scn4bb-203
(1)
|
Ensembl | 502 nt | ||
| mRNA |
scn4bb-204
(1)
|
Ensembl | 1,153 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers