Gene
scn4bb
- ID
- ZDB-GENE-031116-71
- Name
- sodium channel, voltage-gated, type IV, beta b
- Symbol
- scn4bb Nomenclature History
- Previous Names
-
- scn4b.2 (1)
- sb:cb973
- si:ch211-139a5.5
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable sodium channel regulator activity and transmembrane transporter binding activity. Predicted to be involved in cardiac muscle cell action potential involved in contraction; regulation of sodium ion transmembrane transporter activity; and regulation of ventricular cardiac muscle cell membrane repolarization. Predicted to act upstream of or within monoatomic ion transport. Predicted to be located in membrane. Predicted to be part of voltage-gated sodium channel complex. Is expressed in cardiac ventricle; liver; nervous system; and solid lens vesicle. Human ortholog(s) of this gene implicated in long QT syndrome 10. Orthologous to human SCN4B (sodium voltage-gated channel beta subunit 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb973 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| long QT syndrome 10 | Alliance | Atrial fibrillation, familial, 17 | 611819 |
| long QT syndrome 10 | Alliance | Long QT syndrome 10 | 611819 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013106 | Immunoglobulin V-set domain |
| Family | IPR000920 | Myelin P0 protein-related |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin V-set domain | Myelin P0 protein-related |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q06W25
|
232 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
scn4bb-201
(1)
|
Ensembl | 1,876 nt | ||
| mRNA |
scn4bb-202
(1)
|
Ensembl | 645 nt | ||
| mRNA |
scn4bb-203
(1)
|
Ensembl | 502 nt | ||
| mRNA |
scn4bb-204
(1)
|
Ensembl | 1,153 nt |
Interactions and Pathways
No data available
Plasmids
No data available