Gene

ovol1a

ID
ZDB-GENE-031010-37
Name
ovo-like zinc finger 1a
Symbol
ovol1a Nomenclature History
Previous Names
  • ovol1
  • sb:cb956 (1)
  • zgc:171804
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and sequence-specific DNA binding activity. Involved in establishment of protein localization to membrane; neural crest cell migration; and pigment cell development. Localizes to nucleus. Human ortholog(s) of this gene implicated in posterior polymorphous corneal dystrophy 1. Is expressed in several structures, including EVL; digestive system; periderm; prechordal plate; and sensory system. Orthologous to several human genes including OVOL1 (ovo like transcriptional repressor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Piloto et al., 2010
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ovol1a Human Ortholog
No data available
Associated With ovol1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Family IPR027756 Ovo-like
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length Ovo-like Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:F8W4G4 319
UniProtKB:A9JSU5 256
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA ovol1a-201 (1) Havana 2536 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations