Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030902-1
Gene Name: cytochrome P450, family 1, subfamily B, polypeptide 1
Gene Symbol: cyp1b1
Previous Name: zgc:136223
Nomenclature History
GENE EXPRESSION
All Expression Data: 14 figures from 6 publications
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Adult (90d-730d, breeding adult)
  brain, diencephalon, eye, gill (all 13) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-cyp1b1 (1), MO2-cyp1b1 (1)
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Glaucoma 3A, primary open angle, congenital, juvenile, or adult onset 231300
Peters anomaly 604229
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component endoplasmic reticulum (more)
Molecular Function aromatase activity (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001128 (1)
  • InterPro:IPR002401 (1)
  • InterPro:IPR008066 (1)
  • InterPro:IPR017972 (1)
  • PROSITE:PS00086 (1)
  • Pfam:PF00067 (1)
  • EC:1.14.14.1 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cyp1b1-001 (1) 2422
    aberrant processed transcript cyp1b1-002 (1) 3257
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM cyp1b1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cyp1b1 Contained in: [BAC] DKEY-18N13 (1)
    cyp1b1 Encodes: [cDNA] MGC:136223 (1) (order this), MGC:194048 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001145708 (1) 3257 bp
    Genomic GenBank:CT583720 (1) 215665 bp Blast at MegaBLAST
    Polypeptide UniProtKB:B8JKD5 (1) 526 aa
    Sequence Clusters UniGene:85241 (1)
    Sequence Information (all 25)
    OTHER cyp1b1 GENE PAGES
  • Gene:100150054 (1)
  • VEGA:OTTDARG00000027793 (1)
  • Ensembl(Zv9):ENSDARG00000068934 (1)
  • MAPPING INFORMATION
    Chr: 13 Details
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish cyp1b1 13  
    Human CYP1B1 2 (2p22.2)
  • OMIM:601771
  • Gene:1545
  • Mouse Cyp1b1 17 ( 50.30 cM)
  • MGI:88590
  • Gene:13078
  • CITATIONS (45)