Gene
casp8ap2
- ID
- ZDB-GENE-030826-8
- Name
- caspase 8 associated protein 2
- Symbol
- casp8ap2 Nomenclature History
- Previous Names
-
- fc74h10
- FLASH
- wu:fc74h10
- zgc:113449
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable transcription corepressor activity. Predicted to be involved in Fas signaling pathway; activation of cysteine-type endopeptidase activity involved in apoptotic process; and extrinsic apoptotic signaling pathway via death domain receptors. Predicted to act upstream of or within apoptotic signaling pathway. Predicted to be active in PML body and mitochondrion. Orthologous to human CASP8AP2 (caspase 8 associated protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:113449 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | CASP8-associated protein 2 | Gon4l/CASP8AP2, myb-like domain | Homedomain-like superfamily |
|---|---|---|---|---|
|
UniProtKB:F1QD18
|
1995 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
casp8ap2-201
(1)
|
Ensembl | 6,363 nt |
Interactions and Pathways
No data available
Plasmids