Gene
casp6a
- ID
- ZDB-GENE-030825-4
- Name
- caspase 6, apoptosis-related cysteine peptidase a
- Symbol
- casp6a Nomenclature History
- Previous Names
-
- casp6
- caspase-6a (1)
- zgc:112960
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have cysteine-type endopeptidase activity involved in apoptotic process. Predicted to be involved in apoptotic process. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in ovarian carcinoma. Is expressed in several structures, including gut; integument; liver; muscle cell; and solid lens vesicle. Orthologous to human CASP6 (caspase 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016129 | Peptidase family C14A, His active site |
| Domain | IPR001309 | Peptidase C14, p20 domain |
| Domain | IPR002138 | Peptidase C14, caspase non-catalytic subunit p10 |
| Domain | IPR011600 | Peptidase C14, caspase domain |
| Domain | IPR015917 | Peptidase C14A, caspase catalytic domain |
| Homologous_superfamily | IPR029030 | Caspase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Caspase-like domain superfamily | Peptidase C14A, caspase catalytic domain | Peptidase C14, caspase domain | Peptidase C14, caspase non-catalytic subunit p10 | Peptidase C14, p20 domain | Peptidase family C14A, His active site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:F1R2P5
|
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|
UniProtKB:Q52KK6
|
298 |
Interactions and Pathways
No data available
Plasmids
No data available