ZFIN ID: ZDB-GENE-030722-3
Gene Name: slit homolog 1a (Drosophila)
Gene Symbol: slit1a
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 9 publications
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  central nervous system, diencephalon, forebrain, hindbrain dorsal region (all 10) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
la012435Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la012436Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1497 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11050 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12013 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa16176 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa22189 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-slit1a, MO2-slit1a (1), MO3-slit1a (1)
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in: postoptic commissure, retinal ganglion cell axon, retinal ganglion cell cysteine-type endopeptidase activity
    DISEASE ASSOCIATED WITH slit1a HUMAN ORTHOLOG No data available
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process positive regulation of axon extension (more)
    Cellular Component extracellular region (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000152 (1)
  • InterPro:IPR000372 (1)
  • InterPro:IPR000483 (1)
  • InterPro:IPR000742 (1)
  • InterPro:IPR001611 (1)
  • InterPro:IPR001791 (1)
  • InterPro:IPR001881 (1)
  • InterPro:IPR003591 (1)
  • InterPro:IPR003645 (1)
  • InterPro:IPR006207 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR013320 (1)
  • InterPro:IPR018097 (1)
  • InterPro:IPR032675 (1)
  • PROSITE:PS00010 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01185 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS01187 (1)
  • PROSITE:PS01225 (1)
  • PROSITE:PS50025 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS51450 (1)
  • Pfam:PF00008 (1)
  • Pfam:PF01462 (1)
  • Pfam:PF01463 (1)
  • Pfam:PF02210 (1)
  • Pfam:PF12661 (1)
  • Pfam:PF13855 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA slit1a-001 (1) 6008
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM slit1a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    slit1aContained in: [BAC] CH211-178H7 (1) (order this), DKEY-58O21 (1) (order this)
    slit1aEncodes: [cDNA] MGC:195059 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001034968 (1) 6037bp
    Genomic GenBank:BX005147 (1) 147683bp
    Select Tool
    Polypeptide UniProtKB:B3DJM7 (1) 1524aa
    Sequence Clusters UniGene:88478 (1)
    Sequence Information (all 15)
    OTHER slit1a GENE PAGES 
  • Gene:556123 (1)
  • VEGA:OTTDARG00000029347 (1)
  • Ensembl(GRCz10):ENSDARG00000044954 (1)
  • ORTHOLOGY for slit1a (Chr: 13) 
    Species Symbol Chromosome Accession # Evidence
    Human SLIT1 10
  • Gene:6585
  • OMIM:603742
  • HGNC:11085
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Slit1 19
  • MGI:1315203
  • Gene:20562
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (40)