ZFIN ID: ZDB-GENE-030722-3
Gene Name: slit homolog 1a (Drosophila)
Gene Symbol: slit1a
Location: Chr: 13   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 9 publications
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  central nervous system, diencephalon, forebrain, hindbrain dorsal region (all 10) expand
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 1 genotype
Alleles: la012435Tg, la012436Tg, sa11050, sa12013, sa1497 (all 7) expand
Knockdown reagents: MO1-slit1a, MO2-slit1a (1), MO3-slit1a (1)
PHENOTYPE
Data: Fig. 5 from Devine et al., 2008
Observed in: postoptic commissure
GENE ONTOLOGY
Ontology GO Term
Biological Process positive regulation of axon extension (more)
Cellular Component extracellular region (more)
Molecular Function calcium ion binding (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000152 (1)
  • InterPro:IPR000372 (1)
  • InterPro:IPR000483 (1)
  • InterPro:IPR000742 (1)
  • InterPro:IPR001611 (1)
  • InterPro:IPR001791 (1)
  • InterPro:IPR001881 (1)
  • InterPro:IPR003591 (1)
  • InterPro:IPR003645 (1)
  • InterPro:IPR006207 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR013320 (1)
  • InterPro:IPR018097 (1)
  • InterPro:IPR025875 (1)
  • PROSITE:PS00010 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01185 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS01187 (1)
  • PROSITE:PS01225 (1)
  • PROSITE:PS50025 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS51450 (1)
  • Pfam:PF00008 (1)
  • Pfam:PF00560 (1)
  • Pfam:PF01462 (1)
  • Pfam:PF01463 (1)
  • Pfam:PF02210 (1)
  • Pfam:PF12661 (1)
  • Pfam:PF12799 (1)
  • Pfam:PF13855 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA slit1a-001 (1) 6008
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM slit1a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    slit1a Contained in: [BAC] CH211-178H7 (1) (order this), DKEY-58O21 (1)
    slit1a Encodes: [cDNA] MGC:195059 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001034968 (1) 6037 bp
    Genomic GenBank:BX005147 (1) 147683 bp
    Select Tool
    Polypeptide UniProtKB:B3DJM7 (1) 1524 aa
    Sequence Clusters UniGene:88478 (1)
    Sequence Information (all 15)
    OTHER slit1a GENE PAGES
  • Gene:556123 (1)
  • VEGA:OTTDARG00000029347 (1)
  • Ensembl(Zv9):ENSDARG00000044954 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish slit1a 13  
    Human SLIT1 10 (10q23.3-q24)
  • OMIM:603742
  • Gene:6585
  • Mouse Slit1 19 ( 34.99 cM)
  • MGI:1315203
  • Gene:20562
  • Orthology Details
    CITATIONS (37)