ZFIN ID: ZDB-GENE-030722-3
Gene Name: slit homolog 1a (Drosophila)
Gene Symbol: slit1a

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 12 figures from 10 publications
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  central nervous system, diencephalon, diencephalon antero-medial region, forebrain (all 12) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012435Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la012436Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1497 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11050 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12013 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa16176 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22189 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35388 Point Mutation Unknown Splice Site ENU
    Targeting reagents: MO1-slit1a, MO2-slit1a (1), MO3-slit1a (1)
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in: postoptic commissure, retinal ganglion cell axon, retinal ganglion cell cysteine-type endopeptidase activity
    DISEASE ASSOCIATED WITH slit1a HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of axon extension (more)
    Cellular Component extracellular region (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000152 (1)
  • InterPro:IPR000372 (1)
  • InterPro:IPR000483 (1)
  • InterPro:IPR000742 (1)
  • InterPro:IPR001611 (1)
  • InterPro:IPR001791 (1)
  • InterPro:IPR001881 (1)
  • InterPro:IPR003591 (1)
  • InterPro:IPR006207 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR013320 (1)
  • InterPro:IPR018097 (1)
  • InterPro:IPR032675 (1)
  • PROSITE:PS00010 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01185 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS01187 (1)
  • PROSITE:PS01225 (1)
  • PROSITE:PS50025 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS51450 (1)
  • Pfam:PF00008 (1)
  • Pfam:PF01462 (1)
  • Pfam:PF01463 (1)
  • Pfam:PF02210 (1)
  • Pfam:PF12661 (1)
  • Pfam:PF13855 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA slit1a-001 (1) 6008
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM slit1a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    slit1aContained in: [BAC] CH211-178H7 (1) (order this), DKEY-58O21 (1) (order this)
    slit1aEncodes: [cDNA] MGC:195059 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001034968 (1) 6037bp
    Genomic GenBank:BX005147 (1) 147683bp
    Select Tool
    Polypeptide UniProtKB:B3DJM7 (1) 1524aa
    Sequence Clusters UniGene:88478 (1)
    Sequence Information (all 15)
    OTHER slit1a GENE PAGES
  • Gene:556123 (1)
  • VEGA:OTTDARG00000029347 (1)
  • Ensembl(GRCz10):ENSDARG00000044954 (1)
  • ORTHOLOGY for slit1a (Chr: 13)
    Species Symbol Chromosome Accession # Evidence
    Human SLIT1 10
  • Gene:6585
  • OMIM:603742
  • HGNC:11085
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Slit1 19
  • MGI:1315203
  • Gene:20562
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (41)