ZFIN ID: ZDB-GENE-030722-3
Gene Name: slit homolog 1a (Drosophila)
Gene Symbol: slit1a
Location: Chr: 13   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 9 publications
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  central nervous system, diencephalon, forebrain, hindbrain dorsal region (all 10) expand
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: slit1asa1497/sa1497(Tupfel long fin)
Knockdown reagents: MO1-slit1a, MO2-slit1a (1), MO3-slit1a (1)

Allele Type Mutagen Suppliers
la012435Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la012436Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1497 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11050 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa12013 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa16176 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa22189 Point Mutation ENU
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in: postoptic commissure, retinal ganglion cell axon, retinal ganglion cell cysteine-type endopeptidase activity
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of axon extension (more)
    Cellular Component extracellular region (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000152 (1)
  • InterPro:IPR000372 (1)
  • InterPro:IPR000483 (1)
  • InterPro:IPR000742 (1)
  • InterPro:IPR001611 (1)
  • InterPro:IPR001791 (1)
  • InterPro:IPR001881 (1)
  • InterPro:IPR003591 (1)
  • InterPro:IPR003645 (1)
  • InterPro:IPR006207 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR013320 (1)
  • InterPro:IPR018097 (1)
  • InterPro:IPR025875 (1)
  • PROSITE:PS00010 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01185 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS01187 (1)
  • PROSITE:PS01225 (1)
  • PROSITE:PS50025 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS51450 (1)
  • Pfam:PF00008 (1)
  • Pfam:PF00560 (1)
  • Pfam:PF01462 (1)
  • Pfam:PF01463 (1)
  • Pfam:PF02210 (1)
  • Pfam:PF12661 (1)
  • Pfam:PF12799 (1)
  • Pfam:PF13855 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA slit1a-001 (1) 6008
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM slit1a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    slit1a Contained in: [BAC] CH211-178H7 (1) (order this), DKEY-58O21 (1) (order this)
    slit1a Encodes: [cDNA] MGC:195059 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001034968 (1) 6037 bp
    Genomic GenBank:BX005147 (1) 147683 bp
    Select Tool
    Polypeptide UniProtKB:B3DJM7 (1) 1524 aa
    Sequence Clusters UniGene:88478 (1)
    Sequence Information (all 15)
    OTHER slit1a GENE PAGES
  • Gene:556123 (1)
  • VEGA:OTTDARG00000029347 (1)
  • Ensembl(Zv9):ENSDARG00000044954 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish slit1a 13  
    Human SLIT1 10 (10q23.3-q24)
  • OMIM:603742
  • Gene:6585
  • Mouse Slit1 19 ( 34.99 cM)
  • MGI:1315203
  • Gene:20562
  • Orthology Details
    CITATIONS (37)