Gene

msnb

ID

ZDB-GENE-030717-7

Name

moesin b

Symbol

msnb Nomenclature History

Previous Names

msn

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to have actin binding activity. Predicted to localize to cytoskeleton. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human MSN (moesin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Link et al., 2006

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With msnb Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
immunodeficiency 50	Alliance	Immunodeficiency 50	300988

Associated With msnb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019747	FERM conserved site
Domain	IPR000299	FERM domain
Domain	IPR011259	Ezrin/radixin/moesin, C-terminal
Domain	IPR018979	FERM, N-terminal
Domain	IPR018980	FERM, C-terminal PH-like domain
Domain	IPR019748	FERM central domain
Domain	IPR019749	Band 4.1 domain
Domain	IPR041789	ERM family, FERM domain C-lobe
Domain	IPR046810	Ezrin/radixin/moesin, alpha-helical domain
Family	IPR000798	Ezrin/radixin/moesin-like
Family	IPR011174	Ezrin/radixin/moesin
Homologous_superfamily	IPR008954	Moesin tail domain superfamily
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR014352	FERM/acyl-CoA-binding protein superfamily
Homologous_superfamily	IPR029071	Ubiquitin-like domain superfamily
Homologous_superfamily	IPR035963	FERM superfamily, second domain

Domain Details Per Protein

Protein	Length	Band 4.1 domain	ERM family, FERM domain C-lobe	Ezrin/radixin/moesin	Ezrin/radixin/moesin, alpha-helical domain	Ezrin/radixin/moesin, C-terminal	Ezrin/radixin/moesin-like	FERM/acyl-CoA-binding protein superfamily	FERM central domain	FERM conserved site	FERM, C-terminal PH-like domain	FERM domain	FERM, N-terminal	FERM superfamily, second domain	Moesin tail domain superfamily	PH-like domain superfamily	Ubiquitin-like domain superfamily
UniProtKB:A0A8M9PZ73 InterPro	560
UniProtKB:E7F638 InterPro	577

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	msnb-201 (1) Ensembl	Havana	2044 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	msnb-002 (1) Ensembl	Havana	515 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations