Gene

atp11c

ID

ZDB-GENE-030616-51

Name

ATPase phospholipid transporting 11C

Symbol

atp11c Nomenclature History

Previous Names

fb79h04
si:bz1l9.1
wu:fb79h04

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to have ATPase-coupled intramembrane lipid transporter activity. Predicted to be involved in phospholipid translocation. Predicted to localize to several cellular components, including endoplasmic reticulum; recycling endosome; and trans-Golgi network. Orthologous to human ATP11C (ATPase phospholipid transporting 11C).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Hawkey-Noble et al., 2020

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With atp11c Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
X-linked congenital hemolytic anemia	Alliance	?Hemolytic anemia, congenital, X-linked	301015

Associated With atp11c Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR032630	P-type ATPase, C-terminal
Domain	IPR032631	P-type ATPase, N-terminal
Domain	IPR044492	P-type ATPase, haloacid dehalogenase domain
Family	IPR001757	P-type ATPase
Family	IPR006539	P-type ATPase, subfamily IV
Homologous_superfamily	IPR008250	P-type ATPase, A domain superfamily
Homologous_superfamily	IPR023214	HAD superfamily
Homologous_superfamily	IPR023298	P-type ATPase, transmembrane domain superfamily
Homologous_superfamily	IPR023299	P-type ATPase, cytoplasmic domain N
Homologous_superfamily	IPR036412	HAD-like superfamily
PTM	IPR018303	P-type ATPase, phosphorylation site

Domain Details Per Protein

Protein	Length	HAD-like superfamily	HAD superfamily	P-type ATPase	P-type ATPase, A domain superfamily	P-type ATPase, C-terminal	P-type ATPase, cytoplasmic domain N	P-type ATPase, haloacid dehalogenase domain	P-type ATPase, N-terminal	P-type ATPase, phosphorylation site	P-type ATPase, subfamily IV	P-type ATPase, transmembrane domain superfamily
UniProtKB:A0A8M9PUH0 InterPro	1139
UniProtKB:A0A8M3APA8 InterPro	1127
UniProtKB:A0A8M9Q5A3 InterPro	1134
UniProtKB:A0A8M3AGS1 InterPro	1121
UniProtKB:A0A8M9PBR1 InterPro	1121
UniProtKB:A0A8M3AS49 InterPro	1139
UniProtKB:A0A8M9QPH4 InterPro	1134
UniProtKB:A0A8M9Q1J2 InterPro	1127

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	atp11c-201 (1) Ensembl	Ensembl	4,139 nt	Select Tool
mRNA	atp11c-202 (1) Ensembl	Ensembl	411 nt	Select Tool
mRNA	atp11c-203 (1) Ensembl	Ensembl	4,157 nt	Select Tool
mRNA	atp11c-204 (1) Ensembl	Ensembl	3,546 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations