Gene
pold2
- ID
- ZDB-GENE-030616-157
- Name
- polymerase (DNA directed), delta 2, regulatory subunit
- Symbol
- pold2 Nomenclature History
- Previous Names
-
- si:dz150f13.3
- zgc:55633
- zgc:77043
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable DNA binding activity. Predicted to be involved in DNA strand elongation involved in DNA replication. Predicted to act upstream of or within DNA replication. Predicted to be located in nucleus. Predicted to be part of delta DNA polymerase complex. Orthologous to human POLD2 (DNA polymerase delta 2, accessory subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa14006 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | DNA polymerase alpha/delta/epsilon, subunit B | DNA polymerase delta/II small subunit family | DNA polymerase delta subunit 2, C-terminal domain | DNA polymerase delta subunit, OB-fold domain |
|---|---|---|---|---|---|
|
UniProtKB:Q90X40
|
467 | ||||
|
UniProtKB:A0A8M3B257
|
292 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-330C15 | ZFIN Curated Data | |
| Contained in | BAC | CH211-242M24 | ZFIN Curated Data | |
| Contained in | PAC | BUSM1-150F13 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:55633 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:77043 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:191859 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:198403 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:198405 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_213303 (1) | 1662 nt | ||
| Genomic | GenBank:AL591213 (2) | 113551 nt | ||
| Polypeptide | UniProtKB:Q90X40 (1) | 467 aa |
No data available
- Kuil, L.E., Oosterhof, N., Ferrero, G., Mikulášová, T., Hason, M., Dekker, J., Rovira, M., van der Linde, H.C., van Strien, P.M., de Pater, E., Schaaf, G., Bindels, E.M., Wittamer, V., van Ham, T.J. (2020) Zebrafish macrophage developmental arrest underlies depletion of microglia and reveals Csf1r-independent metaphocytes. eLIFE. 9:
- Coimbra, R.S., Weil, D., Brottier, P., Blanchard, S., Levi, M., Hardelin, J.-P., Weissenbach, J., and Petit, C. (2002) A subtracted cDNA library from the zebrafish (Danio rerio) embryonic inner ear. Genome research. 12(6):1007-1011
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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