Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030522-1
Gene Name: cardiac myosin light chain-1
Gene Symbol: cmlc1
Previous Names: laz (1), lazy susan (1), zgc:103441
Nomenclature History
GENE EXPRESSION
All Expression Data: 13 figures from 9 publications
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  anterior lateral plate mesoderm, atrium, cardiac ventricle, heart (all 10) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 3 genotypes
Alleles: m647
Knockdown reagents: MO1-cmlc1 (1), MO2-cmlc1 (1)
PHENOTYPE
Data: 9 figures from 4 publications
Observed in: anatomical system, atrium, cardiac muscle cell sarcomere, cardiac muscle cell (all 11) expand
GENE ONTOLOGY
Ontology GO Term
Biological Process cardiac muscle tissue development (more)
Molecular Function calcium ion binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002048 (1)
  • InterPro:IPR011992 (1)
  • PROSITE:PS50222 (1)
  • Pfam:PF13405 (1)
  • Pfam:PF13499 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cmlc1-001 (1) 796
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM cmlc1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cmlc1 Contained in: [BAC] DKEY-43F11 (1)
    cmlc1 Encodes: [EST] IMAGE:6903402 (1) (order this)
    [cDNA] MGC:103441 (1) (order this), MGC:192170 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131692 (1) 822 bp
    Genomic GenBank:AL845516 (1) 205826 bp Blast at MegaBLAST
    Polypeptide UniProtKB:B0R0F7 (1) 196 aa
    Sequence Clusters UniGene:76021 (1)
    Sequence Information (all 17)
    OTHER cmlc1 GENE PAGES
  • Gene:64671 (1)
  • VEGA:OTTDARG00000018808 (1)
  • Ensembl(Zv9):ENSDARG00000032976 (1)
  • MAPPING INFORMATION
    Chr: 5 Details
    ORTHOLOGY No data available
    CITATIONS (30)