Gene
adarb1b
- ID
- ZDB-GENE-030219-15
- Name
- adenosine deaminase RNA specific B1b
- Symbol
- adarb1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable double-stranded RNA adenosine deaminase activity; double-stranded RNA binding activity; and tRNA-specific adenosine deaminase activity. Predicted to be involved in RNA processing and adenosine to inosine editing. Predicted to be active in cytoplasm and nucleolus. Is expressed in blood island; blood vessel; central nervous system; and immature eye. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human ADARB1 (adenosine deaminase RNA specific B1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with hypotonia, microcephaly, and seizures | 618862 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ADAR2, first double-stranded RNA binding domain | ADAR2, second double-stranded RNA binding domain | Adenosine deaminase/editase | Double-stranded RNA-binding domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q590
|
750 | ||||
|
UniProtKB:E9QJK5
|
699 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adarb1b-201
(1)
|
Ensembl | 2,471 nt | ||
| mRNA |
adarb1b-202
(1)
|
Ensembl | 2,457 nt | ||
| mRNA |
adarb1b-203
(1)
|
Ensembl | 2,199 nt |
Interactions and Pathways
No data available
Plasmids
No data available