Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030219-1
Gene Name: southpaw
Gene Symbol: spaw
Previous Names: ndr3 (2), unm s457, unm t30973, unm_s457, unm_t30973
Location: Chr: 5   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 113 figures from 89 publications
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
  adaxial cell, anterior lateral plate mesoderm, anterior neural rod, diencephalon left side (all 20) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 3 genotypes
Alleles: s457, sa177, t30973
Knockdown reagents: MO1-spaw (1), MO2-spaw (1), MO3-spaw (1)
PHENOTYPE
Data: 13 figures from 11 publications
Observed in: BMP signaling pathway involved in heart development, cardioblast migration, cell migration involved in heart jogging, determination of heart left/right asymmetry (all 23) expand
GENE ONTOLOGY
Ontology GO Term
Biological Process determination of left/right asymmetry in lateral mesoderm (more)
Cellular Component extracellular region (more)
Molecular Function growth factor activity (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001111 (1)
  • InterPro:IPR001839 (1)
  • InterPro:IPR002405 (1)
  • InterPro:IPR015615 (1)
  • InterPro:IPR017948 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS00250 (1)
  • PROSITE:PS51362 (1)
  • Pfam:PF00019 (1)
  • Pfam:PF00688 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA spaw-001 (1) 1263
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM spaw No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    spaw Contained in: [BAC] CH211-173B16 (1) (order this)
    spaw Encodes: [cDNA] MGC:194178 (1) (order this), MGC:194213 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_180967 (1) 1229 bp
    Genomic GenBank:CT033825 (1) 152404 bp
    Select Tool
    Polypeptide UniProtKB:F1QX69 (1) 411 aa
    Sequence Clusters UniGene:88813 (1)
    Sequence Information (all 14)
    OTHER spaw GENE PAGES
  • Gene:338101 (1)
  • VEGA:OTTDARG00000029254 (1)
  • Ensembl(Zv9):ENSDARG00000014309 (1)
  • ORTHOLOGY No data available
    CITATIONS (145)