ZFIN ID: ZDB-GENE-030219-1
Gene Name: southpaw
Gene Symbol: spaw
Previous Names: ndr3 (2), unm s457, unm t30973, unm_s457, unm_t30973
Location: Chr: 5   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 128 figures from 101 publications
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
  adaxial cell, anterior lateral plate mesoderm, anterior neural rod, diencephalon left side (all 26) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 7 Genotypes
Knockdown reagents: MO1-spaw (1), MO2-spaw (1), MO3-spaw (1)

Allele Type Mutagen Suppliers
s457 Point Mutation ENU
sa177 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • t30973 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE
    Data: 23 figures from 15 publications
    Observed in: BMP signaling pathway involved in heart development, cardiac muscle cell cell migration involved in heart formation, cardiac muscle cell, cardioblast migration (all 37) expand
    DISEASE ASSOCIATED WITH spaw HUMAN ORTHOLOG No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process determination of left/right asymmetry in lateral mesoderm (more)
    Cellular Component extracellular region (more)
    Molecular Function growth factor activity (more)
    GO Terms (all 24)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001111 (1)
  • InterPro:IPR001839 (1)
  • InterPro:IPR002405 (1)
  • InterPro:IPR015615 (1)
  • InterPro:IPR017948 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS00250 (1)
  • PROSITE:PS51362 (1)
  • Pfam:PF00019 (1)
  • Pfam:PF00688 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA spaw-001 (1) 1263
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM spaw No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    spaw Contained in: [BAC] CH211-173B16 (1) (order this)
    spaw Encodes: [cDNA] MGC:194178 (1) (order this), MGC:194213 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_180967 (1) 1229 bp
    Genomic GenBank:CT033825 (1) 152404 bp
    Select Tool
    Polypeptide UniProtKB:F1QX69 (1) 411 aa
    Sequence Clusters UniGene:88813 (1)
    Sequence Information (all 14)
    OTHER spaw GENE PAGES
  • Gene:338101 (1)
  • VEGA:OTTDARG00000029254 (1)
  • Ensembl(Zv9):ENSDARG00000014309 (1)
  • ORTHOLOGY No data available
    CITATIONS (158)