ZFIN ID: ZDB-GENE-030219-1
Gene Name: southpaw
Gene Symbol: spaw
Previous Names: ndr3 (2), unm s457, unm t30973, unm_s457, unm_t30973
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 137 figures from 108 publications
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
  adaxial cell, anterior lateral plate mesoderm, anterior neural rod, diencephalon left side (all 37) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
s457 Point Mutation Unknown Start Loss ENU
sa177 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • t30973 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: CRISPR1-spaw (2), MO1-spaw (1), MO2-spaw (1), MO3-spaw (1)
    PHENOTYPE
    Data: 28 figures from 17 publications
    Observed in: atrioventricular canal development, atrioventricular valve blood, atrioventricular valve, atrioventricular valve morphogenesis (all 43) expand
    DISEASE ASSOCIATED WITH spaw HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process determination of left/right asymmetry in lateral mesoderm (more)
    Cellular Component extracellular region (more)
    Molecular Function growth factor activity (more)
    GO Terms (all 25)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001111 (1)
  • InterPro:IPR001839 (1)
  • InterPro:IPR002405 (1)
  • InterPro:IPR015615 (1)
  • InterPro:IPR017948 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS00250 (1)
  • PROSITE:PS51362 (1)
  • Pfam:PF00019 (1)
  • Pfam:PF00688 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA spaw-001 (1) 1263
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM spaw No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    spawContained in: [BAC] CH211-173B16 (1) (order this)
    spawEncodes: [cDNA] MGC:194178 (1) (order this), MGC:194213 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_180967 (1) 1229bp
    Genomic GenBank:CT033825 (1) 152404bp
    Select Tool
    Polypeptide UniProtKB:F1QX69 (1) 411aa
    Sequence Clusters UniGene:88813 (1)
    Sequence Information (all 14)
    OTHER spaw GENE PAGES
  • Gene:338101 (1)
  • VEGA:OTTDARG00000029254 (1)
  • Ensembl(GRCz10):ENSDARG00000014309 (1)
  • ORTHOLOGY for spaw (Chr: 5)No data available
    CITATIONS (171)