ZFIN ID: ZDB-GENE-030131-994
Gene Name: RAD21 homolog (S. pombe) a
Gene Symbol: rad21a
Previous Names: rad21, wu:fb55d02, wu:fb93f04
Location: Chr: 16   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 9 figures from 4 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55325]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, caudal tuberculum proliferative region, chondrocranium, ciliary marginal zone (all 37) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 6 Genotypes
Knockdown reagents: MO1-rad21a (1), MO2-rad21a (1), MO3-rad21a (1)

Allele Type Mutagen Suppliers
hi2529Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • nz171 Point Mutation ENU
    PHENOTYPE
    Data: 10 figures from 6 publications
    Observed in: blood circulation, brain, cell spindle, cell death (all 20) expand

    Phenotype of Human Orthologue OMIM Phenotype ID
    Cornelia de Lange syndrome 4 614701
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mitotic sister chromatid cohesion (more)
    Cellular Component nuclear chromosome (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006909 (1)
  • InterPro:IPR006910 (1)
  • InterPro:IPR023093 (1)
  • Pfam:PF04824 (1)
  • Pfam:PF04825 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ottdart00000061990 (1) 2622
    ncRNA ottdart00000061991 (1) 709
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIES
    Ab1-rad21 (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rad21a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    rad21a Contained in: [BAC] CH73-179G5 (1) (order this), DKEY-210P14 (1) (order this)
    rad21a Encodes: [EST] fb55d02, fb93f04
    [cDNA] MGC:55325 (1) (order this), MGC:191732 (1) (order this)
    rad21a Has Artifact: [EST] fc73h09
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199595 (1) 2615 bp
    Genomic GenBank:BX005205 (1) 164219 bp
    Select Tool
    Polypeptide UniProtKB:Q6TEL1 (1) 643 aa
    Sequence Clusters UniGene:94731 (1)
    Sequence Information (all 22)
    OTHER rad21a GENE PAGES
  • Gene:322275 (1)
  • VEGA:OTTDARG00000042889 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish rad21a 16  
    Human RAD21 8 (8q24)
  • OMIM:606462
  • Gene:5885
  • Mouse Rad21 15 ( 19.54 cM)
  • MGI:108016
  • Gene:19357
  • Orthology Details
    CITATIONS (27)