ZFIN ID: ZDB-GENE-030131-994
Gene Name: RAD21 cohesin complex component a
Gene Symbol: rad21a
Previous Names: rad21, wu:fb55d02, wu:fb93f04
Location: Chr: 16   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 9 figures from 4 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55325]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, caudal tuberculum proliferative region, chondrocranium, ciliary marginal zone (all 37) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 6 Genotypes
Knockdown reagents: MO1-rad21a (1), MO2-rad21a (1), MO3-rad21a (1), MO4-rad21a (1)

Allele Type Mutagen Suppliers
hi2529Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • nz171 Point Mutation ENU
    PHENOTYPE
    Data: 11 figures from 7 publications
    Observed in: blood circulation, brain, cell spindle, cell death (all 22) expand
    DISEASE ASSOCIATED WITH rad21a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Cornelia de Lange syndrome Cornelia de Lange syndrome 4 614701
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process enteric nervous system development (more)
    Cellular Component nuclear chromosome (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006909 (1)
  • InterPro:IPR006910 (1)
  • InterPro:IPR023093 (1)
  • Pfam:PF04824 (1)
  • Pfam:PF04825 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ottdart00000061990 (1) 2622
    ncRNA ottdart00000061991 (1) 709
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIES
    Ab1-rad21 (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rad21a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    rad21a Contained in: [BAC] CH73-179G5 (1) (order this), DKEY-210P14 (1) (order this)
    rad21a Encodes: [EST] fb55d02, fb93f04
    [cDNA] MGC:55325 (1) (order this), MGC:191732 (1) (order this)
    rad21a Has Artifact: [EST] fc73h09
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199595 (1) 2615 bp
    Genomic GenBank:BX005205 (1) 164219 bp
    Select Tool
    Polypeptide UniProtKB:Q6TEL1 (1) 643 aa
    Sequence Clusters UniGene:94731 (1)
    Sequence Information (all 22)
    OTHER rad21a GENE PAGES
  • Gene:322275 (1)
  • VEGA:OTTDARG00000042889 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish rad21a 16  
    Human RAD21 8 (8q24)
  • OMIM:606462
  • Gene:5885
  • Mouse Rad21 15 ( 19.54 cM)
  • MGI:108016
  • Gene:19357
  • Orthology Details
    CITATIONS (28)