Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-994
Gene Name: RAD21 homolog (S. pombe) a
Gene Symbol: rad21a
Previous Names: rad21, wu:fb55d02, wu:fb93f04
Nomenclature History
GENE EXPRESSION
All Expression Data: 9 figures from 4 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55325]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, midbrain hindbrain boundary, oocyte, otic vesicle (all 15) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 6 genotypes
Alleles: hi2529Tg, nz171
Knockdown reagents: MO1-rad21a (1), MO2-rad21a (1), MO3-rad21a (1)
PHENOTYPE
Data: 10 figures from 6 publications
Observed in: blood circulation, brain, cell spindle, cell death (all 20) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Cornelia de Lange syndrome 4 614701
GENE ONTOLOGY
Ontology GO Term
Biological Process mitotic sister chromatid cohesion (more)
Cellular Component nuclear chromosome (more)
Molecular Function sequence-specific DNA binding (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006909 (1)
  • InterPro:IPR006910 (1)
  • InterPro:IPR023093 (1)
  • Pfam:PF04824 (1)
  • Pfam:PF04825 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA rad21a-001 (1) 2625
    ncRNA rad21a-002 (1) 709
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIES
    Ab1-rad21 (1)
    CONSTRUCTS WITH SEQUENCES FROM rad21a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    rad21a Contained in: [BAC] DKEY-210P14 (1)
    rad21a Encodes: [EST] fb55d02, fb93f04
    [cDNA] MGC:55325 (1) (order this), MGC:191732 (1) (order this)
    rad21a Has Artifact: [EST] fc73h09
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199595 (1) 2615 bp
    Genomic GenBank:BX005205 (1) 164219 bp
    Select Tool
    Polypeptide UniProtKB:Q6TEL1 (1) 643 aa
    Sequence Clusters UniGene:94731 (1)
    Sequence Information (all 19)
    OTHER rad21a GENE PAGES
  • Gene:322275 (1)
  • VEGA:OTTDARG00000021138 (1)
  • Ensembl(Zv9):ENSDARG00000086515 (1)
  • MAPPING INFORMATION
    Chr: 16 Details View Map: Merged   Individual Panels
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish rad21a 16  
    Human RAD21 8 (8q24)
  • OMIM:606462
  • Gene:5885
  • Mouse Rad21 15 ( 19.54 cM)
  • MGI:108016
  • Gene:19357
  • CITATIONS (27)