ZFIN ID: ZDB-GENE-030131-994
Gene Name: RAD21 cohesin complex component a
Gene Symbol: rad21a
Previous Names: rad21, wu:fb55d02, wu:fb93f04
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 9 figures from 4 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55325]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, caudal tuberculum proliferative region, chondrocranium, ciliary marginal zone (all 37) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi2529Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • nz171 Point Mutation Unknown Unknown ENU
    Targeting reagents: MO1-rad21a (1), MO2-rad21a (1), MO3-rad21a (1), MO4-rad21a (1)
    PHENOTYPE
    Data: 32 figures from 9 publications
    Observed in: atrioventricular valve, atrium blood, blood circulation, brain (all 44) expand
    DISEASE ASSOCIATED WITH rad21a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Cornelia de Lange syndrome Cornelia de Lange syndrome 4 614701
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process enteric nervous system development (more)
    Cellular Component nuclear chromosome (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006909 (1)
  • InterPro:IPR006910 (1)
  • InterPro:IPR011991 (1)
  • InterPro:IPR023093 (1)
  • Pfam:PF04824 (1)
  • Pfam:PF04825 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ottdart00000061990 (1) 2622
    ncRNA ottdart00000061991 (1) 709
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIES
    Ab1-rad21 (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM rad21a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    rad21aContained in: [BAC] CH73-179G5 (1) (order this), DKEY-210P14 (1) (order this)
    rad21aEncodes: [EST] fb55d02, fb93f04
    [cDNA] MGC:55325 (1) (order this), MGC:191732 (1) (order this)
    rad21aHas Artifact: [EST] fc73h09
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199595 (1) 2615bp
    Genomic GenBank:BX005205 (1) 164219bp
    Select Tool
    Polypeptide UniProtKB:Q6TEL1 (1) 643aa
    Sequence Clusters UniGene:94731 (1)
    Sequence Information (all 20)
    OTHER rad21a GENE PAGES
  • Gene:322275 (1)
  • VEGA:OTTDARG00000042889 (1)
  • Ensembl(GRCz10):ENSDARG00000006092 (1)
  • ORTHOLOGY for rad21a (Chr: 16)
    Species Symbol Chromosome Accession # Evidence
    Human RAD21 8
  • Gene:5885
  • OMIM:606462
  • HGNC:9811
  • Amino acid sequence comparison (5)
    Conserved genome location (synteny) (1)
    Mouse Rad21 15
  • MGI:108016
  • Gene:19357
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (32)