Gene

dennd6b

ID

ZDB-GENE-030131-9382

Name

DENN/MADD domain containing 6B

Symbol

dennd6b Nomenclature History

Previous Names

fam116b
fj67e07
wu:fj67e07
zgc:55619

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to have Rab guanyl-nucleotide exchange factor activity. Predicted to localize to recycling endosome. Is expressed in central nervous system; cranial ganglion; retina; telencephalon; and yolk syncytial layer. Orthologous to human DENND6B (DENN domain containing 6B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:55619 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dennd6b Human Ortholog

No data available

Associated With dennd6b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR018307	AVL9/DENND6 domain
Domain	IPR037516	Tripartite DENN domain
Family	IPR024224	DENND6

Domain Details Per Protein

Protein	Length	AVL9/DENND6 domain	DENND6	Tripartite DENN domain
UniProtKB:Q803T4 InterPro	575
UniProtKB:A0A8M2BBU9 InterPro	530

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	dennd6b-201 (1) Ensembl	Havana	3123 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations