Gene
cfp
- ID
- ZDB-GENE-030131-9247
- Name
- complement factor properdin
- Symbol
- cfp Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Involved in immune response. Human ortholog(s) of this gene implicated in X-linked properdin deficiency. Is expressed in several structures, including cardiovascular system; digestive system; eye; gonad; and neutrophil. Orthologous to human CFP (complement factor properdin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Zhang et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| X-linked properdin deficiency | Alliance | Properdin deficiency, X-linked | 312060 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR052065 | Complement and asymmetry regulator |
| Homologous_superfamily | IPR036383 | Thrombospondin type-1 (TSP1) repeat superfamily |
| Repeat | IPR000884 | Thrombospondin type-1 (TSP1) repeat |
| Repeat | IPR049536 | Properdin, thrombospondin type 1 repeat 0 |
| Repeat | IPR054019 | Properdin, thrombospondin type 1 C-terminal |
Domain Details Per Protein
| Protein | Length | Complement and asymmetry regulator | Properdin, thrombospondin type 1 C-terminal | Properdin, thrombospondin type 1 repeat 0 | Thrombospondin type-1 (TSP1) repeat | Thrombospondin type-1 (TSP1) repeat superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:B0S697
|
437 |
Interactions and Pathways
No data available
Plasmids
No data available