Gene

septin2

ID
ZDB-GENE-030131-911
Name
septin 2
Symbol
septin2 Nomenclature History
Previous Names
  • sept2
  • nedd5 (1)
  • wu:fb52g01
  • wu:fb99a01
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable GTPase activity and molecular adaptor activity. Predicted to be involved in cilium assembly; cytoskeleton-dependent cytokinesis; and regulation of exocytosis. Predicted to act upstream of or within cell division. Predicted to be located in several cellular components, including ciliary membrane; cleavage furrow; and midbody. Predicted to be part of septin complex. Predicted to be active in cell division site; cytoskeleton; and synaptic vesicle. Is expressed in artery; notochord; and vein. Orthologous to human SEPTIN2 (septin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With septin2 Human Ortholog
No data available
Associated With septin2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR030379 Septin-type guanine nucleotide-binding (G) domain
Family IPR008113 Septin 2
Family IPR016491 Septin
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length P-loop containing nucleoside triphosphate hydrolase Septin Septin 2 Septin-type guanine nucleotide-binding (G) domain
UniProtKB:F1QQN9 369
UniProtKB:A0A8M3B088 356
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA sept2-201 (1) Ensembl 1,396 nt
mRNA sept2-202 (1) Ensembl 2,260 nt
mRNA sept2-203 (1) Ensembl 2,299 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations