Gene
hagh
- ID
- ZDB-GENE-030131-8921
- Name
- hydroxyacylglutathione hydrolase
- Symbol
- hagh Nomenclature History
- Previous Names
-
- fa66a03
- wu:fa66a03
- zgc:73161 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable hydroxyacylglutathione hydrolase activity. Predicted to be involved in glutathione metabolic process. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Is expressed in gut; intestinal bulb; and liver. Orthologous to human HAGH (hydroxyacylglutathione hydrolase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6893408 (3 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| [Glyoxalase II deficiency] | 614033 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001279 | Metallo-beta-lactamase |
| Domain | IPR032282 | Hydroxyacylglutathione hydrolase, C-terminal domain |
| Domain | IPR035680 | Hydroxyacylglutathione hydrolase, MBL domain |
| Family | IPR017782 | Hydroxyacylglutathione hydrolase |
| Homologous_superfamily | IPR036866 | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like |
Domain Details Per Protein
| Protein | Additional Resources | Length | Hydroxyacylglutathione hydrolase | Hydroxyacylglutathione hydrolase, C-terminal domain | Hydroxyacylglutathione hydrolase, MBL domain | Metallo-beta-lactamase | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PEU7 | InterPro | 162 | |||||
| UniProtKB:Q6P963 | InterPro | 303 |
Interactions and Pathways
No data available
Plasmids
No data available