Gene

hapln2

ID

ZDB-GENE-030131-8089

Name

hyaluronan and proteoglycan link protein 2

Symbol

hapln2 Nomenclature History

Previous Names

fj51g03
si:dkey-235h8.3
wu:fj51g03

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Enables identical protein binding activity. Predicted to be involved in central nervous system development and skeletal system development. Predicted to act upstream of or within cell adhesion. Predicted to be located in plasma membrane. Predicted to be active in extracellular space; perineuronal net; and synapse. Is expressed in otic placode; otic vesicle; and pharyngeal arch. Orthologous to human HAPLN2 (hyaluronan and proteoglycan link protein 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from Thisse et al., 2008

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cssl:d833 (8 images)
cssl:d236 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hapln2 Human Ortholog

No data available

Associated With hapln2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000538	Link domain
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013106	Immunoglobulin V-set domain
Family	IPR050691	Hyaluronan-binding Proteoglycan
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR016186	C-type lectin-like/link domain superfamily
Homologous_superfamily	IPR016187	C-type lectin fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily