Gene
nell2b
- ID
- ZDB-GENE-030131-8026
- Name
- neural EGFL like 2b
- Symbol
- nell2b Nomenclature History
- Previous Names
-
- fj47f01
- si:dkey-234l24.6
- wu:fj47f01
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable heparin binding activity and protein kinase C binding activity. Predicted to act upstream of or within phosphorylation. Predicted to be active in cytoplasm and extracellular space. Is expressed in nervous system and pharyngeal arch. Orthologous to human NELL2 (neural EGFL like 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Zhao et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018097 | EGF-like calcium-binding, conserved site |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001007 | VWFC domain |
| Domain | IPR001791 | Laminin G domain |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR024731 | EGF domain |
| Domain | IPR048287 | Thrombospondin-like, N-terminal domain |
| Domain | IPR049883 | NOTCH1 EGF-like calcium-binding domain |
| Family | IPR051586 | Protein kinase C-binding NELL |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| PTM | IPR000152 | EGF-type aspartate/asparagine hydroxylation site |
Domain Details Per Protein
| Protein | Length | Concanavalin A-like lectin/glucanase domain superfamily | EGF domain | EGF-like calcium-binding, conserved site | EGF-like calcium-binding domain | EGF-like domain | EGF-type aspartate/asparagine hydroxylation site | Growth factor receptor cysteine-rich domain superfamily | Laminin G domain | NOTCH1 EGF-like calcium-binding domain | Protein kinase C-binding NELL | Thrombospondin-like, N-terminal domain | VWFC domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QV50
|
815 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nell2b-201
(1)
|
Ensembl | 5,154 nt | ||
| mRNA |
nell2b-202
(1)
|
Ensembl | 4,637 nt |
Interactions and Pathways
No data available
Plasmids
No data available