Gene
il12bb
- ID
- ZDB-GENE-030131-7937
- Name
- interleukin 12B, b
- Symbol
- il12bb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have cytokine binding activity and cytokine receptor activity. Predicted to localize to external side of plasma membrane and receptor complex. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; primary immunodeficiency disease; and salmonellosis. Is expressed in digestive system; gill; immune system; and muscle. Orthologous to human IL12B (interleukin 12B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 29 | Alliance | Immunodeficiency 29, mycobacteriosis | 614890 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Fibronectin type III superfamily | Immunoglobulin-like fold | Interleukin-12 beta | Interleukin-12 beta, central domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PV11
|
314 | ||||
|
UniProtKB:A0A8M9Q7B2
|
314 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
il12bb-201
(1)
|
Havana | 920 nt |
Interactions and Pathways
No data available
Plasmids
No data available