Gene
cdh15
- ID
- ZDB-GENE-030131-780
- Name
- cadherin 15, type 1, M-cadherin (myotubule)
- Symbol
- cdh15 Nomenclature History
- Previous Names
-
- fb48f12
- wu:fb48f12
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have cadherin binding activity; calcium ion binding activity; and cytoskeletal protein binding activity. Predicted to be involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell-cell adhesion mediated by cadherin; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to localize to adherens junction; catenin complex; and cell surface. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 3. Is expressed in adaxial cell; musculature system; pectoral fin; and somite. Orthologous to human CDH15 (cadherin 15).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu141 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Cortés et al., 2003
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 3 | Alliance | Intellectual developmental disorder, autosomal dominant 3 | 612580 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cadherin | Cadherin conserved site | Cadherin-like | Cadherin-like superfamily | Cadherin, Y-type LIR-motif | Catenin binding domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:E9QEL7
|
792 |
Interactions and Pathways
No data available
Plasmids
No data available