Gene
sulf2b
- ID
- ZDB-GENE-030131-775
- Name
- sulfatase 2b
- Symbol
- sulf2b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have N-acetylglucosamine-6-sulfatase activity and glycosaminoglycan binding activity. Predicted to be involved in several processes, including glomerular basement membrane development; positive regulation of vascular endothelial growth factor production; and regulation of signal transduction. Predicted to localize to cell surface; endoplasmic reticulum; and plasma membrane. Is expressed in several structures, including central nervous system; head; neural rod; segmental plate; and somite. Orthologous to human SULF2 (sulfatase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Schenk et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR024607 | Sulfatase, conserved site |
| Domain | IPR000917 | Sulfatase, N-terminal |
| Domain | IPR004868 | DNA-directed DNA polymerase, family B, mitochondria/virus |
| Domain | IPR024609 | Extracellular sulfatase, C-terminal |
| Family | IPR006172 | DNA-directed DNA polymerase, family B |
| Family | IPR014615 | Extracellular sulfatase |
| Homologous_superfamily | IPR012337 | Ribonuclease H-like superfamily |
| Homologous_superfamily | IPR017850 | Alkaline-phosphatase-like, core domain superfamily |
| Homologous_superfamily | IPR023211 | DNA polymerase, palm domain superfamily |
| Homologous_superfamily | IPR036397 | Ribonuclease H superfamily |
| Homologous_superfamily | IPR043502 | DNA/RNA polymerase superfamily |
Domain Details Per Protein
| Protein | Length | Alkaline-phosphatase-like, core domain superfamily | DNA-directed DNA polymerase, family B | DNA-directed DNA polymerase, family B, mitochondria/virus | DNA polymerase, palm domain superfamily | DNA/RNA polymerase superfamily | Extracellular sulfatase | Extracellular sulfatase, C-terminal | Ribonuclease H-like superfamily | Ribonuclease H superfamily | Sulfatase, conserved site | Sulfatase, N-terminal |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PKK2
|
1293 | |||||||||||
|
UniProtKB:A0A8M9P505
|
867 | |||||||||||
|
UniProtKB:A0A8M9PSW4
|
881 | |||||||||||
|
UniProtKB:Q6EF98
|
885 | |||||||||||
|
UniProtKB:A0A8M3B5Z5
|
1179 | |||||||||||
|
UniProtKB:A0A8M6YXM3
|
1044 | |||||||||||
|
UniProtKB:A0A8M9PKK6
|
856 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sulf2b-201
(1)
|
Ensembl | 5,114 nt | ||
| mRNA |
sulf2b-202
(1)
|
Ensembl | 962 nt | ||
| mRNA |
sulf2b-203
(1)
|
Ensembl | 2,604 nt | ||
| mRNA |
sulf2b-204
(1)
|
Ensembl | 321 nt |
Interactions and Pathways
No data available
Plasmids
No data available