Gene
lgals3a
- ID
- ZDB-GENE-030131-7667
- Name
- lectin, galactoside binding soluble 3a
- Symbol
- lgals3a Nomenclature History
- Previous Names
-
- lgals3
- fb13c09
- fk60g08
- si:ch211-67f24.5
- wu:fb13c09
- wu:fk60g08 (1)
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable IgE binding activity; disaccharide binding activity; and laminin binding activity. Predicted to be involved in several processes, including leukocyte chemotaxis; negative regulation of extrinsic apoptotic signaling pathway; and positive regulation of calcium ion import. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in extracellular region. Predicted to be part of spliceosomal complex. Predicted to be active in several cellular components, including extracellular space; immunological synapse; and nucleus. Is expressed in brain and liver. Human ortholog(s) of this gene implicated in asthma. Orthologous to human LGALS3 (galectin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Wiweger et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Concanavalin A-like lectin/glucanase domain superfamily | Galectin, carbohydrate recognition domain | Galectin-like |
|---|---|---|---|---|
|
UniProtKB:A0A8N7UTJ9
|
368 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lgals3a-201
(1)
|
Ensembl | 999 nt | ||
| mRNA |
lgals3a-202
(1)
|
Ensembl | 1,283 nt | ||
| mRNA |
lgals3a-204
(1)
|
Ensembl | 1,170 nt | ||
| ncRNA |
lgals3a-003
(1)
|
Ensembl | 869 nt |
Interactions and Pathways
No data available
Plasmids
No data available