Gene
srgn
- ID
- ZDB-GENE-030131-7127
- Name
- serglycin
- Symbol
- srgn Nomenclature History
- Previous Names
-
- fk86b08
- si:dkey-226b20.6
- wu:fk86b08 (1)
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Is expressed in neutrophil. Orthologous to human SRGN (serglycin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR007455 | Serglycin |
Domain Details Per Protein
| Protein | Additional Resources | Length | Serglycin |
|---|---|---|---|
| UniProtKB:B8A5H9 | InterPro | 158 |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-226B20 | ZFIN Curated Data | |
| Encodes | EST | fk86b08 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001171612 (1) | 1396 nt | ||
| Genomic | GenBank:BX546482 (1) | 206949 nt | ||
| Polypeptide | UniProtKB:B8A5H9 (1) | 158 aa |
- Jia-Xin, H., Song'en, X., Wen-Qing, Z., Wei, L. (2024) The interaction of Pu.1 and cMyb in zebrafish neutrophil development. Yi chuan = Hereditas. 46:319332319-332
- Rayamajhi, D., Ege, M., Ukhanov, K., Ringers, C., Zhang, Y., Jung, I., D'Gama, P.P., Li, S.S., Cosacak, M.I., Kizil, C., Park, H.C., Yaksi, E., Martens, J.R., Brody, S.L., Jurisch-Yaksi, N., Roy, S. (2024) The forkhead transcription factor Foxj1 controls vertebrate olfactory cilia biogenesis and sensory neuron differentiation. PLoS Biology. 22:e3002468e3002468
- Ye, Y., Yang, X., Li, F., Liu, W., Zhang, W., Huang, Z. (2022) c-myb is involved in CML progression and is a therapeutic target in the zebrafish CML model. Animal models and experimental medicine. 7(2):136-144
- Huang, Z., Chen, K., Chi, Y., Jin, H., Li, L., Zhang, W., Xu, J., Zhang, Y. (2021) Runx1 regulates zebrafish neutrophil maturation via synergistic interaction with c-Myb. The Journal of biological chemistry. 296:100272
- Jerison, E.R., Quake, S.R. (2020) Heterogeneous T cell motility behaviors emerge from a coupling between speed and turning in vivo. eLIFE. 9:
- Tsata, V., Möllmert, S., Schweitzer, C., Kolb, J., Möckel, C., Böhm, B., Rosso, G., Lange, C., Lesche, M., Hammer, J., Kesavan, G., Beis, D., Guck, J., Brand, M., Wehner, D. (2020) A switch in pdgfrb+ cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord. Developmental Cell. 56(4):509-524.e9
- Chestnut, B., Sumanas, S. (2019) Zebrafish etv2 knock-in line labels vascular endothelial and blood progenitor cells. Developmental Dynamics : an official publication of the American Association of Anatomists. 249(2):245-261
- Jin, H., Huang, Z., Chi, Y., Wu, M., Zhou, R., Zhao, L., Xu, J., Zhen, F., Lan, Y., Li, L., Zhang, W., Wen, Z., Zhang, Y. (2016) cMyb acts in parallel and cooperatively with Cebp1 to regulate neutrophil maturation in zebrafish. Blood. 128(3):415-26
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Wang, K., Fang, X., Ma, N., Lin, Q., Huang, Z., Liu, W., Xu, M., Chen, X., Zhang, W., Zhang, Y. (2015) Myeloperoxidase-deficient Zebrafish show an Augmented Inflammatory Response to Challenge with Candida albicans. Fish & shellfish immunology. 44(1):109-16
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