Gene
capzb
- ID
- ZDB-GENE-030131-7023
- Name
- capping actin protein of muscle Z-line subunit beta
- Symbol
- capzb Nomenclature History
- Previous Names
-
- wu:fk65f06
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity. Involved in muscle cell development and neural crest cell migration. Predicted to localize to F-actin capping protein complex. Used to study cleft palate. Is expressed in fin bud; head; pharyngeal arch; and somite. Orthologous to human CAPZB (capping actin protein of muscle Z-line subunit beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Mukherjee et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| cleft palate | capzbhi1858bTg/hi1858bTg | standard conditions | Mukherjee et al., 2016 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019771 | F-actin capping protein, beta subunit, conserved site |
| Family | IPR001698 | F-actin-capping protein subunit beta |
| Homologous_superfamily | IPR037282 | F-actin-capping protein subunit alpha/beta |
| Homologous_superfamily | IPR042276 | F-actin-capping protein subunit alpha/beta, domain 2 |
| Homologous_superfamily | IPR043175 | F-actin-capping protein subunit beta, N-terminal domain |
Domain Details Per Protein
| Protein | Length | F-actin capping protein, beta subunit, conserved site | F-actin-capping protein subunit alpha/beta | F-actin-capping protein subunit alpha/beta, domain 2 | F-actin-capping protein subunit beta | F-actin-capping protein subunit beta, N-terminal domain |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AUB3
|
274 | |||||
|
UniProtKB:Q7SXP1
|
273 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available