Gene

ncl

ID
ZDB-GENE-030131-6986
Name
nucleolin
Symbol
ncl Nomenclature History
Previous Names
  • fa12d03
  • wu:fa12d03
  • zgc:152810
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have mRNA binding activity. Involved in heart looping; rRNA processing; and rRNA transcription. Predicted to localize to cytoplasm; nucleus; and ribonucleoprotein complex. Is expressed in cardiac ventricle. Orthologous to human NCL (nucleolin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ncl Human Ortholog
No data available
Associated With ncl Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR034230 Nucleolin, RNA recognition motif 1
Domain IPR034233 Nucleolin, RNA recognition motif 2
Domain IPR034234 Nucleolin, RNA recognition motif 3
Domain IPR034235 Nucleolin, RNA recognition motif 4
Family IPR050374 RRT5/SRSF/Splicing Factor SR
Family IPR050502 Eukaryotic RNA-binding
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
Domain Details Per Protein
Protein Length Eukaryotic RNA-binding Nucleolin, RNA recognition motif 1 Nucleolin, RNA recognition motif 2 Nucleolin, RNA recognition motif 3 Nucleolin, RNA recognition motif 4 Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA recognition motif domain RRT5/SRSF/Splicing Factor SR
UniProtKB:F1R6L6 705
UniProtKB:B8JLQ3 704
UniProtKB:A0A8M2BHX2 657
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
aberrant processed transcript ncl-203 (1) Ensembl 2,671 nt
mRNA ncl-201 (1) Ensembl 2,826 nt
mRNA ncl-202 (1) Ensembl 3,219 nt
ncRNA ncl-003 (1) Ensembl 710 nt
ncRNA ncl-004 (1) Ensembl 456 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations