Gene
ndufa10
- ID
- ZDB-GENE-030131-670
- Name
- NADH:ubiquinone oxidoreductase subunit A10
- Symbol
- ndufa10 Nomenclature History
- Previous Names
-
- wu:fb39a11
- zgc:73344
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial matrix and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Predicted to be active in cytoplasm. Is expressed in several structures, including alar plate midbrain region; gut; immature eye; myotome; and nervous system. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 22. Orthologous to human NDUFA10 (NADH:ubiquinone oxidoreductase subunit A10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6910474 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nuclear type mitochondrial complex I deficiency 22 | Alliance | Mitochondrial complex I deficiency, nuclear type 22 | 618243 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Deoxynucleoside kinase domain | Deoxyribonucleoside Kinase | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|
|
UniProtKB:Q6PBM0
|
355 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ndufa10-201
(1)
|
Ensembl | 1,350 nt | ||
| mRNA |
ndufa10-202
(1)
|
Ensembl | 1,309 nt |
Interactions and Pathways
No data available
Plasmids
No data available