Gene
zfhx2
- ID
- ZDB-GENE-030131-6699
- Name
- zinc finger homeobox 2
- Symbol
- zfhx2 Nomenclature History
- Previous Names
-
- wu:fa03a11
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of neuron differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Marsili syndrome. Orthologous to human ZFHX2 (zinc finger homeobox 2).
- Genome Resources
-
- Alliance (1)
- Gene:795005 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Marsili syndrome | Alliance | ?Marsili syndrome | 147430 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017970 | Homeobox, conserved site |
| Domain | IPR001356 | Homeodomain |
| Domain | IPR013087 | Zinc finger C2H2-type |
| Family | IPR051968 | Zinc finger homeobox transcription regulators |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
| Homologous_superfamily | IPR036236 | Zinc finger C2H2 superfamily |
Domain Details Per Protein
| Protein | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Zinc finger C2H2 superfamily | Zinc finger C2H2-type | Zinc finger homeobox transcription regulators |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M1PYY4
|
1529 | ||||||
|
UniProtKB:A0A8M9PUD5
|
1512 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance