Gene

wdr48b

ID

ZDB-GENE-030131-6622

Name

WD repeat domain 48b

Symbol

wdr48b Nomenclature History

Previous Names

wdr48
fk50c12
wu:fd19a04
wu:fk50c12
zgc:66229 (1)

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable DNA binding activity; deubiquitinase activator activity; and ubiquitin binding activity. Predicted to be involved in double-strand break repair via homologous recombination and positive regulation of double-strand break repair via homologous recombination. Predicted to act upstream of or within DNA repair. Predicted to be located in nucleus. Orthologous to human WDR48 (WD repeat domain 48).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:66229 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With wdr48b Human Ortholog

No data available

Associated With wdr48b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019775	WD40 repeat, conserved site
Family	IPR021772	WDR48/Bun107
Family	IPR051246	WD repeat-containing protein 48
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat
Repeat	IPR020472	G-protein beta WD-40 repeat