Gene
toporsa
- ID
- ZDB-GENE-030131-6401
- Name
- topoisomerase I binding, arginine/serine-rich a
- Symbol
- toporsa Nomenclature History
- Previous Names
-
- topors
- si:ch211-145b13.4
- wu:fc21e07 (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have ubiquitin protein ligase activity. Involved in retina layer formation. Human ortholog(s) of this gene implicated in retinitis pigmentosa 31. Is expressed in photoreceptor inner segment layer; retinal ganglion cell layer; retinal inner nuclear layer; and retinal outer nuclear layer. Orthologous to human TOPORS (TOP1 binding arginine/serine rich protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chakarova et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Chakarova et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 31 | Alliance | Retinitis pigmentosa 31 | 609923 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site |
|---|---|---|---|---|
|
UniProtKB:A0A8M1P6B6
|
999 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
toporsa-201
(1)
|
Ensembl | 3,579 nt | ||
| mRNA |
toporsa-202
(1)
|
Ensembl | 775 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-topors | monoclonal | Mouse |
|
Abnova
|
1 |
Plasmids
No data available