Gene

cenpj

ID
ZDB-GENE-030131-6323
Name
centromere protein J
Symbol
cenpj Nomenclature History
Previous Names
  • CPAP (1)
  • si:dkey-46k9.9
  • wu:fi46g11 (1)
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have tubulin binding activity. Predicted to be involved in centriole elongation and cilium assembly. Predicted to localize to centriole; centrosome; and nucleus. Human ortholog(s) of this gene implicated in Seckel syndrome 4; primary autosomal recessive microcephaly; and primary autosomal recessive microcephaly 6. Orthologous to human CENPJ (centromere protein J).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cenpj Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
primary autosomal recessive microcephaly 6 Alliance Microcephaly 6, primary, autosomal recessive 608393
Seckel syndrome 4 Alliance ?Seckel syndrome 4 613676
Associated With cenpj Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR009852 Centromere protein J, C-terminal domain
Family IPR026581 T-complex protein 10 family
Homologous_superfamily IPR047002 T-complex protein 10, C-terminal domain superfamily
Domain Details Per Protein
Protein Length Centromere protein J, C-terminal domain T-complex protein 10, C-terminal domain superfamily T-complex protein 10 family
UniProtKB:E7FCY1 1124
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA cenpj-201 (1) Havana 3611 nt
mRNA cenpj-202 (1) Ensembl 5956 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations