Gene
cpap
- ID
- ZDB-GENE-030131-6323
- Name
- centrosome assembly and centriole elongation protein
- Symbol
- cpap Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Enables protein domain specific binding activity. Predicted to be involved in centriole elongation and cilium assembly. Predicted to act upstream of or within cell division and regulation of centriole replication. Predicted to be active in centriole and centrosome. Human ortholog(s) of this gene implicated in Seckel syndrome 4; primary autosomal recessive microcephaly; and primary autosomal recessive microcephaly 6. Orthologous to human CENPJ (centromere protein J).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary autosomal recessive microcephaly 6 | Alliance | Microcephaly 6, primary, autosomal recessive | 608393 |
| Seckel syndrome 4 | Alliance | ?Seckel syndrome 4 | 613676 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Centromere protein J, C-terminal domain | T-complex protein 10, C-terminal domain superfamily | T-complex protein 10 family |
|---|---|---|---|---|
|
UniProtKB:E7FCY1
|
1124 |
Interactions and Pathways
No data available
Plasmids
No data available